Fig. 2

Gut microbiome impact on host metabolic phenotypes in different dietary fibers. Phenotypes were measured after 6 weeks colonization and 4 weeks of specific dietary fiber exposure (~ 15 weeks old). a Epididymal fat pad weight expressed a percentage of body weight (n = 7–10/community/diet). b Liver triglycerides levels (n = 7–10/community/diet). c Serum glucose levels (arbitrary units) as measured by UPLC/MS/MS (untargeted metabolomics platform; n = 6/community/diet). Wilcoxon rank sum test was conducted to examine whether two samples are likely to derive from the same population. Box plots represent median, interquartile range, minimum and maximum value in the data, and potential outliers. *P < 0.05, ns = not significant. SubA, magenta; SubB, yellow