Fig. 6
From: Genomic reconstruction of fossil and living microorganisms in ancient Siberian permafrost
Key functional genes involved in the repair of DNA and protein damage and survival under cold, osmotic, and oxidative stresses present (red) in MAGs. Gene abbreviations: protein l-isoaspartyl/d-aspartyl o-methyltransferase (PIMT), methionine sulfoxide reductase (MsrA), uracil-DNA glycosylase (UDG), DNA mismatch repair protein (MutS), DNA replication and repair protein (RecF), cold shock protein (CspA), choline dehydrogenase (betA), betaine aldehyde dehydrogenase (betB), choline sulfatase (betC), glycine betaine/proline ABC transporter (ProV), glycine betaine/proline betaine transport system permease protein (ProW), Glycine betaine/carnitine transport binding protein (GbuC), osmoprotectant ABC transporter ATP-binding protein (OpuAA), glycine betaine transport system permease protein (OpuAB), glycine betaine-binding protein (OpuAC), osmoregulated proline transporter (OpuE), choline transport ATP-binding protein (OpuBA), choline transport system permease protein (OpuBB), carnitine transport ATP-binding protein (OpuCA), carnitine transport permease protein (OpuCB), carnitine transport binding protein (OpuCC), carnitine transport permease protein (OpuCD), ectoine/5-hydroxyectoine-binding periplasmic protein (UehA), osmoprotectant import ATP-binding proteins (osmV), and aquaporin (Aqp). The MAGs highlighted in blue represent the potentially living microbial populations inferred from DNA damage in both iDNA and eDNA fractions