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Fig. 4 | Microbiome

Fig. 4

From: The pregnane X receptor drives sexually dimorphic hepatic changes in lipid and xenobiotic metabolism in response to gut microbiota in mice

Fig. 4

Gut microbiota-dependent changes in hepatic lipid and xenobiotic metabolism are controlled by PXR in male mice. a Hepatic gene expression assessed by qPCR. b Relative abundance of hepatic fatty acids. c Hepatic neutral lipid quantification. d Hepatic gene expression assessed by qPCR. e [14C]-testosterone hydroxylated metabolites obtained from incubation of 14C-testosterone with hepatic microsomes (n = 5 per group). f Glutathione S-transferase-specific activities assessed in hepatic cytosolic fractions (n = 5 per group)

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Microbiome

ISSN: 2049-2618

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