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Fig. 3 | Microbiome

Fig. 3

From: The pregnane X receptor drives sexually dimorphic hepatic changes in lipid and xenobiotic metabolism in response to gut microbiota in mice

Fig. 3

Sexually dimorphic changes in hepatic gene expression associated with microbiota depletion depends on PXR. a Experimental design. ATB antibiotics. b Number of genes regulated in ATB-treated vs. control mice. c Venn diagram representing the number of genes regulated in ATB vs. control mice. d Venn diagram representing the number of genes overexpressed in ATB vs. control males. e Pathway enrichment analysis of the 303 hepatic genes overexpressed in ATB-treated Pxr+/+ males. f Venn diagram representing the number of genes overexpressed in ATB vs. control females. g Venn diagram representing the number of genes underexpressed in ATB vs. control males. h Pathway enrichment analysis of the 111 hepatic genes underexpressed in ATB-treated Pxr+/+ males. i Venn diagram representing the number of genes underexpressed in ATB vs. control females

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Microbiome

ISSN: 2049-2618

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