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Fig. 3 | Microbiome

Fig. 3

From: An atlas of the tissue and blood metagenome in cancer reveals novel links between bacteria, viruses and cancer

Fig. 3

Patient clusters defined by detected taxa can be identified across all patients and in cancer-type subgroups. a t-SNE visualization of all tumor tissue samples color coded by project using the log2-transformed RPPB of all detected non-phage taxa as input variables. bh t-SNE visualizations of single cancer subgroup tumor tissues (b bone cancer, c chronic lymphocytic leukemia, d esophageal cancer, e liver cancer, f pancreatic adenocarcinoma, g prostate adenocarcinoma, h renal cancer). Different colors indicate the k-means clusters of samples to indicate if k-means clustering and t-SNE visualization results in comparable sample groupings (Supplementary Figure 4). Log2-transformed RPPB of all detected non-phage taxa were used as input variables for t-SNE visualization. Dimension 1 and dimension 2 is shown on the x- and y-axis, respectively. Cluster 4*, Pseudomonas sp., Serratia sp., and Salmonella enterica; Cluster 2**, Pseudomonas sp., Serratia sp., Salmonella enterica, Parvibaculum lavamentivorans, and Human Herpesvirus 5; Cluster 5***, Thauera sp. MZ1T, Cupriavidus metallidurans, and Pseudomonas mendocina

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