From: Constraining PERMANOVA and LDM to within-set comparisons by projection improves the efficiency of analyses of matched sets of microbiome data
p-value for testing the
Number of OTUs
community-level hypothesis
detected at FDR 10%
permanovaFL
LDM
DESeq2
Without adjustment of APOE
0.0001
168
66
With adjustment of APOE
0.0069
0.0159
0