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Fig. 2 | Microbiome

Fig. 2

From: Intestinal mycobiota in health and diseases: from a disrupted equilibrium to clinical opportunities

Fig. 2

Potential mechanism of gut mycrobiota in gut-brain axis. (a) Gut mycobiota modulates the expression of genes in kynurenine pathway and associated micro-RNAs (miRNAs) in the hippocampus in a sex-dependent manner. (b) In MS, high Candida spp. burden is detected in peripheral blood and cerebrospinal fluid. (c) Patients with SC have a changed gut mycobiota alpha diversity and higher abundance of Chaetomium. (d) Candida kefyr supplement in gut is beneficial to alleviate EAE. MS, multiple sclerosis; SC, schizophrenia; EAE, experimental autoimmune encephalomyelitis. Arrows represent activation and horizontal lines represent suppression

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