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Fig. 5 | Microbiome

Fig. 5

From: Revealing taxon-specific heavy metal-resistance mechanisms in denitrifying phosphorus removal sludge using genome-centric metaproteomics

Fig. 5

Enriched functions and associating core functioning microbes at the high-pressure stages. Circles refer to significantly upexpressed (red) and downexpressed (blue) ontologies in heavy metal-treated groups estimated by GSEA. Those with Jaccard combined overlap > 0.25 are automatically clustered (by dashed lines) and summarized using Cytoscape application clusterMaker2 and WordCloud, respectively. Rounded squares indicate the core-functioning microbes that contributed the most to the changes of their linked (by solid lines) functions. The number inside the square is the ID number of the corresponding metagenome-assembled genome (MAG). The solid line’s width reflects the number of associations between the microbe and the ontologies within the cluster. For clarity, only associations > half of the number of ontologies in each cluster are shown (full data is available in Additional file 4). a Cd treated. b Ni treated. c Cr treated

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