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Table 1 Characteristics of patients at baseline (time of intervention)

From: Fecal microbiota transplantation to maintain remission in Crohn’s disease: a pilot randomized controlled study

 Whole population (n = 17)Sham transplantation (n = 9)Fecal transplantation (n = 8)p value (sham vs FMT)
Age (years)34.0 [29.0; 37.0]34.0 [33.0; 52.0]31.5 [27.5; 36.5]0.10
 Male9 (52.9)4 (44.4)5 (62.5)0.64
 Female8 (47.1)5 (55.6)3 (37.5)
BMI (kg/m2)22.3 [19.8; 23.3]22.7 [22.3; 23.3]21.0 [18.6; 22.9]0.15
 Smoking, never/past/active6 (35.3)/6 (35.3)/5 (29.4)3 (33.3)/4 (44.4)/2 (22.2)3 (37.5)/2 (25.0)/3 (37.5)0.7
 Disease duration (years)9 [5; 15]11 [8; 15]8.5 [4; 12.8]0.19
 Montreal, L2/L37 (41.2)/10 (58.8)5 (55.6)/4 (44.4)2 (25.0)/6 (75.0)0.33
Hemoglobin (g/L)138 [121; 142]138 [121; 142]134 [116; 147]0.46
White cell count (109/L)10.9 [9.3; 12.8]12.4 [10.0; 13.3]10.1 [8.6; 11.3]0.06
Platelet (109/L)338.0 [278.0; 405.0]346.0 [280.0; 385.0]292.5 [275.5; 493.5]0.42
CRP (mg/L)3.0 [3.0; 3.1]3.0 [3.0; 4.2]3.0 [3.0; 3.0]0.31
Albumin (g/L)40.7 [39.4; 42.7]40.5 [39.4; 42.5]41.4 [39.6; 44.0]0.27
Fecal calprotectin (ug/g)102.0 [40.0; 157.0]117.0 [45.0; 177.3]53.5 [38.0; 112.0]0.22
Previous azathioprine treatment10 (58.8)6 (66.6)4 (50.0)0.49
Previous anti-TNF therapy5 (29.4)3 (33.3)2 (25.0)0.71
Previous other biological therapy3 (17.7)2 (22.2)1 (12.5)0.60
History of intestinal resection2 (11.8)1 (11.1)1 (12.5)0.92
HBI score2.0 [0.0; 3.0]2.0 [0.0; 3.0]1.5 [0.5; 2.5]0.35
CDAI score62.0 [41.0; 109.0]54.0 [35.0 ; 103.0]65.5 [51.5; 173.5]0.16
CDEIS score4.6 [0.2; 10.5]1.6 [0.0; 6.0]7.1 [3.5; 12.2]0.062
  1. Categorical parameters indicated as n (%) and continuous values indicated as P50 [P25; P75]. Quantitative variables were compared using a non-parametric Wilcoxon rank-sum tests. Qualitative variables were compared using Fisher’s exact test
  2. BMI body mass index, CRP C reactive protein, HBI Harvey Bradshaw Index, CDAI Crohn’s disease activity index, CDEIS Crohn’s Disease Endoscopic Index of Severity