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Fig. 4 | Microbiome

Fig. 4

From: Gastric bypass surgery in a rat model alters the community structure and functional composition of the intestinal microbiota independently of weight loss

Fig. 4

Functional structure of the microbiota. a Beta diversity of protein groups based on NMDS analysis (n = 5) (P calculated by PERMANOVA). b Beta diversity of metabolite concentrations from untargeted metabolomics based on NMDS analysis (cecum content RYGB n = 8 and sham n = 4; colon content RYGB n = 8 and sham n = 7) (P calculated by PERMANOVA). c Log2 fold change of bile acid concentrations detected in the colon content (RYGB n = 8 and sham n = 7). CA = cholic acid, CDCA = chenodeoxycholic acid, DCA = deoxycholic acid, GCA = glycocholic acid, GCDCA = glycochenodeoxycholic acid, GDCA = glycodeoxycholic acid, GLCA = glycolithocholic acid, GUDCA = glycoursodeoxycholic acid, HDCA = hyodeoxycholic acid, LCA = lithocholic acid, MCA(a) = alpha-muricholic acid, MCA(b) = beta-muricholic acid, MCA(c) = gamma-muricholic acid, TCA = taurocholic acid, TCDCA = taurochenodeoxycholic acid, TDCA = taurodeoxycholic acid, TLCA = taurolithocholic acid, TMCA(a + b) = tauromuricholic acid (alpha+beta), TUDCA = tauroursodeoxycholic acid (P have all been adjusted for multi-testing using the Benjamini-Hochberg method; ****P < .0001, ***P < .001, **P < .01, *P < .05)

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