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Table 5 List of pathways significantly enriched by the list of regulators

From: A gene co-association network regulating gut microbial communities in a Duroc pig population

Ingenuity canonical pathways −log(P value) Ratio Genes
Osteoarthritis pathway 3.13 0.019 RUNX2,SMAD4,SOX9,TCF4
TGF-β signaling 3.07 0.031 RUNX2,SMAD4,TFE3
Role of osteoblasts, osteoclasts, and chondrocytes in rheumatoid arthritis 3.07 0.018 NFATC3,RUNX2,SMAD4,TCF4
Glucocorticoid receptor signaling 2.4 0.012 NCOR1,NFATC3,SMAD4,STAT1
VDR/RXR activation 2 0.022 NCOR1,RUNX2
BMP signaling pathway 1.93 0.024 RUNX2,SMAD4
Colorectal cancer metastasis signaling 1.89 0.012 SMAD4,STAT1,TCF4
Regulation of IL-2 expression in activated and anergic T lymphocytes 1.89 0.023 NFATC3,SMAD4
Senescencepathway 1.79 0.011 ELF2,NFATC3,SMAD4
Mouse embryonic stem cell pluripotency 1.77 0.019 SMAD4,TCF4
Pancreatic adenocarcinoma signaling 1.72 0.018 SMAD4,STAT1
Neuroinflammation signaling pathway 1.69 0.010 NFATC3,NFE2L2,STAT1
Th1 pathway 1.64 0.016 NFATC3,STAT1
Human embryonic stem cell pluripotency 1.55 0.015 SMAD4,TCF4
Aryl hydrocarbon receptor signaling 1.5 0.014 NFE2L2,TP73
Factors promoting cardiogenesis in vertebrates 1.47 0.013 SMAD4,TCF4
HOTAIR regulatory pathway 1.41 0.012 KMT2C,TCF4
Protein kinase A signaling 1.38 0.008 NFATC3,SMAD4,TCF4
Th1 and Th2 activation pathway 1.36 0.013 NFATC3,STAT1
Wnt/β-catenin signaling 1.35 0.012 SOX9,TCF4
T cell exhaustion signaling pathway 1.34 0.011 NFATC3,STAT1
IL-22 signaling 1.34 0.042 STAT1
Role of JAK family kinases in IL-6-type cytokine signaling 1.32 0.040 STAT1
ERK/MAPK signaling 1.3 0.010 ELF2,STAT1
Hepatic fibrosis/hepatic stellate cell activation 1.3 0.011 SMAD4,STAT1