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Fig. 5 | Microbiome

Fig. 5

From: Antibiotic-associated dysbiosis affects the ability of the gut microbiota to control intestinal inflammation upon fecal microbiota transplantation in experimental colitis models

Fig. 5

Gut microbiota composition and metabolomics analysis of the antibiotics-conditioned human fecal samples used for the ex vivo experiments. a Mean relative abundance at genus level of the antibiotics-conditioned human gut microbiota. All genera with relative abundance < 0.5% are reported together and labeled as “others.” b Significantly different taxa identified in the antibiotics-conditioned human gut microbiota. Exact p values are shown; unpaired t test. c Partial least square discriminant analysis showing clustered fecal water samples according to the type of antibiotic treatment. d Metabolites that differentiate samples according to treatment by variable important in projection (VIP) scores. e Normalized concentrations of metabolites with the highest discriminative power (VIP score > 1.5) for the classification of samples according to the type of treatment. f One-way analysis of variance; red dots indicate the significant metabolites (p < 0.05) after FDR-correction. g Normalized concentration of butyric acid as measured in FW samples. *p < 0.05, **p < 0.01, *** < 0.001; unpaired t test

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Microbiome

ISSN: 2049-2618

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