TY - JOUR AU - Mukherjee, Chiranjit AU - Moyer, Christina O. AU - Steinkamp, Heidi M. AU - Hashmi, Shahr B. AU - Beall, Clifford J. AU - Guo, Xiaohan AU - Ni, Ai AU - Leys, Eugene J. AU - Griffen, Ann L. PY - 2021 DA - 2021/02/23 TI - Acquisition of oral microbiota is driven by environment, not host genetics JO - Microbiome SP - 54 VL - 9 IS - 1 AB - The oral microbiota is acquired very early, but the factors shaping its acquisition are not well understood. Previous studies comparing monozygotic (MZ) and dizygotic (DZ) twins have suggested that host genetics plays a role. However, all twins share an equal portion of their parent’s genome, so this model is not informative for studying parent-to-child transmission. We used a novel study design that allowed us to directly examine the genetics of transmission by comparing the oral microbiota of biological versus adoptive mother-child dyads. SN - 2049-2618 UR - https://doi.org/10.1186/s40168-020-00986-8 DO - 10.1186/s40168-020-00986-8 ID - Mukherjee2021 ER -