Skip to main content

Table 1 Baseline characteristics of participants

From: High-dose saccharin supplementation does not induce gut microbiota changes or glucose intolerance in healthy humans and mice

Total, n (M/F)

Placebo

Saccharin

Lactisole

Sac + Lac

P value

11 (3/8)

13 (4/9)

12 (2/10)

10 (5/5)

Age, year

24.91 ± 1.59

28.91 ± 2.60

32.92 ± 2.78

28.80 ± 2.91

0.199

Height, cm

166.61 ± 2.37

169.03 ± 3.31

164.54 ± 1.92

172.53 ± 2.23

0.494

Weight, kg

59.00 ± 1.81

64.52 ± 3.49

62.13 ± 1.90

66.57 ± 2.64

0.305

BMI, kg/m2

21.29 ± 0.62

22.40 ± 0.53

22.93 ± 0.47

22.38 ± 0.78

0.261

Glucose, mg/dL

87.55 ± 2.40

92.00 ± 2.41

91.63 ± 2.64

90.00 ± 1.23

0.519

Triglycerides, mg/dL

72.36 ± 7.93

71.82 ± 13.88

87.42 ± 12.85

65.70 ± 7.57

0.605

Total cholesterol, mg/dL

166.91 ± 9.38

163.82 ± 10.09

182.33 ± 8.25

154.60 ± 7.47

0.333

HDL, mg/dL

66.55 ± 4.12

57.55 ± 3.74

62.58 ± 4.60

64.80 ± 3.96

0.236

LDL, mg/dL

85.91 ± 7.92

91.82 ± 7.47

102.25 ± 7.29

76.50 ± 9.24

0.162

Cholesterol:HDL ratio

2.58 ± 0.18

2.95 ± 0.27

3.08 ± 0.28

2.49 ± 0.20

0.103

LDL:HDL ratio

1.36 ± 0.17

1.67 ± 0.22

1.77 ± 0.25

1.26 ± 0.19

0.115

  1. All values are mean ± SEM. Baseline differences between groups were assessed by ANCOVA using sex as covariate
  2. M/F male/female, BMI body mass index, HDL high-density cholesterol, LDL low-density cholesterol, AUC area under the curve