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Table 1 Baseline characteristics of participants

From: High-dose saccharin supplementation does not induce gut microbiota changes or glucose intolerance in healthy humans and mice

Total, n (M/F) Placebo Saccharin Lactisole Sac + Lac P value
11 (3/8) 13 (4/9) 12 (2/10) 10 (5/5)
Age, year 24.91 ± 1.59 28.91 ± 2.60 32.92 ± 2.78 28.80 ± 2.91 0.199
Height, cm 166.61 ± 2.37 169.03 ± 3.31 164.54 ± 1.92 172.53 ± 2.23 0.494
Weight, kg 59.00 ± 1.81 64.52 ± 3.49 62.13 ± 1.90 66.57 ± 2.64 0.305
BMI, kg/m2 21.29 ± 0.62 22.40 ± 0.53 22.93 ± 0.47 22.38 ± 0.78 0.261
Glucose, mg/dL 87.55 ± 2.40 92.00 ± 2.41 91.63 ± 2.64 90.00 ± 1.23 0.519
Triglycerides, mg/dL 72.36 ± 7.93 71.82 ± 13.88 87.42 ± 12.85 65.70 ± 7.57 0.605
Total cholesterol, mg/dL 166.91 ± 9.38 163.82 ± 10.09 182.33 ± 8.25 154.60 ± 7.47 0.333
HDL, mg/dL 66.55 ± 4.12 57.55 ± 3.74 62.58 ± 4.60 64.80 ± 3.96 0.236
LDL, mg/dL 85.91 ± 7.92 91.82 ± 7.47 102.25 ± 7.29 76.50 ± 9.24 0.162
Cholesterol:HDL ratio 2.58 ± 0.18 2.95 ± 0.27 3.08 ± 0.28 2.49 ± 0.20 0.103
LDL:HDL ratio 1.36 ± 0.17 1.67 ± 0.22 1.77 ± 0.25 1.26 ± 0.19 0.115
  1. All values are mean ± SEM. Baseline differences between groups were assessed by ANCOVA using sex as covariate
  2. M/F male/female, BMI body mass index, HDL high-density cholesterol, LDL low-density cholesterol, AUC area under the curve