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Fig. 4 | Microbiome

Fig. 4

From: High-dose saccharin supplementation does not induce gut microbiota changes or glucose intolerance in healthy humans and mice

Fig. 4

Treatment effects on gut microbial diversity and composition (genus) in mice. a Alpha diversity indices (Chao1, Shannon, and Simpson) pre- and post-treatment (lines connect data from the same mouse; detailed statistics, Supp. Table.7). b Nonmetric multidimensional scaling (NMDS) plots of Bray-Curtis dissimilarities between all groups pre- and post-treatment, or c within each group (lines connect data from the same participant). d Within-subject Bray-Curtis dissimilarity (paired pre-post) for each treatment group (detailed statistics of beta diversity, Supp. Table.8). e Average values (arbitrary units) of pre-post compositional changes (Δ) at the genus level for each treatment (detailed statistics, Supp. Table.9). For a, two-way ANOVA repeated measures, p value of time x treatment effect. For b, c, PERMANOVA p value. For d, Kruskal-Wallis p value. W water, S saccharin

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Microbiome

ISSN: 2049-2618

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