Skip to main content
Fig. 3 | Microbiome

Fig. 3

From: High-dose saccharin supplementation does not induce gut microbiota changes or glucose intolerance in healthy humans and mice

Fig. 3

Treatment effects on gut microbial diversity and composition (genus) in humans. a Alpha diversity indices (Chao1, Shannon, and Simpson) pre- and post-treatment (lines connect data from the same participant; detailed statistics, Supp. Table.3). b Nonmetric multidimensional scaling (NMDS) plots of Bray-Curtis dissimilarities between all groups pre- and post-treatment, or c within each treatment group (lines connect data from the same participant). d Within-subject Bray-Curtis dissimilarity (paired pre-post) for each treatment group (detailed statistics of beta diversity, Supp. Table.4). e Average values (arbitrary units) of pre-post compositional changes (Δ) at the genus level for each treatment (detailed statistics, Supp. Table.5). For a, two-way ANOVA repeated measures, p value of time x treatment effect. For b, c, PERMANOVA p value. For d, ANOVA p value

Back to article page

Microbiome

ISSN: 2049-2618

Contact us