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Fig. 1 | Microbiome

Fig. 1

From: Re-purposing software for functional characterization of the microbiome

Fig. 1

Transformation of GO hierarchy into a reference functional hierarchy tree structure. Here, GO terms are represented as nodes. a Histogram to show the frequency of the distance of each node from the root LCF of the entire molecular function ontology domain. b Histogram to show the frequency of the number of parents for each node also known as in-degree. c Histogram to show the frequency of the number of children or child terms directly associated with each node also known as out-degree if this number is >‚ÄČ1. Most nodes have only one parent. In cases where a node has 2 parent terms (second most common scenario), we show the most frequently encountered situation and our resolution strategy for this using a pictorial representation (d) and an actual example (e). f Showing the distance from each node to the root from our exploration of different tree building methods including DFS (depth-first search), BFS (breadth-first search) and in the cases where we have more than two parents and random single parents are selected (we repeated this 10 times, RND_1-RND_10)

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