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Fig. 7 | Microbiome

Fig. 7

From: A semi-tryptic peptide centric metaproteomic mining approach and its potential utility in capturing signatures of gut microbial proteolysis

Fig. 7

Location-specific alterations of gut microbial proteolytic motif in the MLI metaproteome of IBD. a and d ascending colon, b and e descending colon, and c and f terminal ileum. Hierarchical clustering analysis (a–c) and partial least squares discriminant analysis (PLS-DA, d–f) of altered amino acid frequencies around the cleavage site in IBD. Group averages are shown in the heatmap. Dunn-Bonferroni post hoc analysis following Kruskal-Wallis test was employed to detect significant difference among three groups (CD, Ctrl, and UC). *P < 0.05 versus Ctrl; **P < 0.01 versus Ctrl; ***P < 0.001 versus Ctrl; #P < 0.05 (CD versus UC); ##P < 0.01 (CD versus UC); ###P < 0.001 (CD versus UC)

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Microbiome

ISSN: 2049-2618

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