Fig 4From: A semi-tryptic peptide centric metaproteomic mining approach and its potential utility in capturing signatures of gut microbial proteolysisCorrelation analysis between gut microbial proteolysis pattern, composition, and protease expression. Principal coordinates analysis (PCoA) of metagenome (a) and microbial protease/peptidase transcriptome (b) is based on Bray-Curtis distance. Correlations between microbial proteolytic signatures (PCo1-PCo3 of semi-tryptic peptide LFQ), microbiome composition (n = 272, c), and protease/peptidase expression (n = 184, d) were calculated using Spearman’s rank correlation based on PCo1-PCo3 of metagenome and metatranscriptome, respectively. Only significant correlations with coefficient > 0.2 or < −0.2 (P < 0.05) are shown in c and d. The P value for each correlated pair is in parenthesesBack to article page