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Fig. 4 | Microbiome

Fig. 4

From: Modulating gut microbiota in a mouse model of Graves’ orbitopathy and its impact on induced disease

Fig. 4

Gut microbiome modification modulates orbital tissue abnormalities in GO mouse model. The orbits of mice were fixed, paraffin embedded, and consecutive slices of the middle orbital area were stained with H&E and evaluated for a brown adipose tissue (BAT); representative images are shown, magnification × 10. b BAT as the percentage of the total fat area. c Atrophic fibers in extra orbital muscles; representative images are shown, magnification × 20, arrows indicate areas with atrophic fibers. d atrophic fibers/total muscle fiber area (a.u.). Data are presented as mean ± standard error of the mean. Multiplicity adjusted P values are marked as ***P < 0.001, **P < 0.01, *P < 0.05 (two-way ANOVA)

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