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Fig. 4 | Microbiome

Fig. 4

From: Shifts in microbial diversity, composition, and functionality in the gut and genital microbiome during a natural SIV infection in vervet monkeys

Fig. 4

Microbiome across stages of SIV infection in vervets. a PCoA colored by stages of SIV infection. P values are adjusted for collection site, gender, and age. b Alpha diversity as presented by Shannon index across different body sites and SIV stages. c Distance box plots comparing distances within a particular SIV stage (i.e., all within) and between SIV infection states across different sample types. The first boxplot contains the distances between all samples that are within the same category, i.e., within negative samples, within acutely infected samples and within chronically infected (all within). The subsequent boxplots represent the distances between all samples in different categories: all chronic samples vs all negative samples, all chronic samples vs. all acute samples, and all negative samples vs. all acute samples. The microbiome samples comprise of the fecal samples (11 SIV negative, 4 acutely infected, 23 chronically infected), rectal samples (41 SIV negative, 11 acutely infected, 43 chronically infected), vaginal samples (10 SIV negative, 6 acutely infected, 30 chronically infected), and penile samples (9 SIV negative, 2 acutely infected, 8 chronically infected). *Indicates comparisons with a p value < 0.05

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