From: β-glucan attenuates cognitive impairment via the gut-brain axis in diet-induced obese mice
KO functional categories | ||||||
---|---|---|---|---|---|---|
Level_1 | Level_2 | Con mean% (SD%) | HFFD mean% (SD%) | HFBG mean% (SD%) | Con vs HFFD p value | HFBG vs HFFD p value |
Cellular processes | Cell motility | 3.491 (0.316) | 4.891 (0.530) | 3.084 (1.207) | 0.008 | _ |
Cellular processes | Cell growth and death | 0.583 (0.013) | 0.559 (0.026) | 0.596 (0.055) | _ | 0.019 |
Cellular processes | Transport and catabolism | 0.585 (0.042) | 0.419 (0.028) | 0.626 (0.065) | 0.008 | 0.016 |
Genetic information processing | Translation | 6.214 (0.205) | 5.767 (0.271) | 6.503 (0.645) | _ | 0.032 |
Genetic information processing | Transcription | 3.149 (0.085) | 3.526 (0.108) | 2.943 (0.388) | 0.015 | _ |
Genetic information processing | Folding, sorting, and degradation | 2.675 (0.074) | 2.475 (0.157) | 2.778 (0.333) | _ | 0.016 |
Environmental information processing | Signal transduction | 2.123 (0.083) | 2.694 (0.130) | 2.000 (0.328) | 0.012 | 0.032 |
Metabolism | Amino acid metabolism | 11.09 (0.226) | 10.490 (0.370) | 11.311 (0.750) | _ | 0.032 |
Metabolism | Energy metabolism | 6.565 (0.169) | 6.134 (0.325) | 6.812 (0.684) | _ | 0.016 |
Metabolism | Metabolism of cofactors and vitamins | 4.793 (0.117) | 4.618 (0.177) | 4.915 (0.404) | _ | 0.016 |
Metabolism | Glycan biosynthesis and metabolism | 3.402 (0.204) | 2.666 (0.137) | 3.592 (0.430) | 0.008 | 0.016 |
Metabolism | Xenobiotics biodegradation and metabolism | 1.787 (0.051) | 1.929 (0.028) | 1.724 (0.087) | 0.016 | 0.001 |
Human diseases | Neurodegenerative diseases | 0.175 (0.007) | 0.181 (0.008) | 0.172 (0.004) | 0.027 | 0.032 |
Organismal systems | Environmental adaptation | 0.186 (0.011) | 0.218 (0.005) | 0.177 (0.015) | 0.016 | 0.032 |
Cellular processes | Cell motility | 3.491 (0.316) | 4.891 (0.530) | 3.084 (1.207) | 0.008 | _ |
Cellular processes | Cell growth and death | 0.583 (0.013) | 0.559 (0.026) | 0.596 (0.055) | _ | 0.019 |