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Fig. 7 | Microbiome

Fig. 7

From: Disruption of ruminal homeostasis by malnutrition involved in systemic ruminal microbiota-host interactions in a pregnant sheep model

Fig. 7

SFR inactivated signal transduction in the ruminal epithelial cells and inhibited cell proliferation. a Schematic plot of signal transduction involved in JAK3-STAT2 and PI3K-AKT signaling pathways. Light red, upregulated; light green, downregulated. b DEGs related to JAK3-STAT2 and PI3K-AKT signaling pathway in RNA sequencing. c DEGs related to DNA replication and cell cycle in RNA sequencing. d Genes related to cyclins and cyclin-dependent kinases in quantitative real-time PCR. Data were presented as the mean with SEM. DEGs were selected based on FDR < 0.05 and FC > 1.5 or < 0.67 (n = 5 per group). Pound key of STAT2 indicated that P < 0.05 and FDR > 0.05. The difference of gene expression in quantitative real-time PCR was identified by independent sample t test (n = 8 per group), and asterisk indicated the significant difference (P < 0.05)

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