Fig. 6

Effect of FMT from adult and old mice on locomotor and explorative activity and anxiety-related behaviour. Open field test did not show significant difference in the distance travelled by both FMT-aged and FMT-adult was observed when compared to the untreated control group indicating no significant motor impairments of the animals (Fig. 4a). However, FMT-aged mice displayed a tendency to prefer the periphery or the corners of the arena instead of the centre (Fig. 4b). The representative tracks of movement patterns are depicted in Fig. 4c–e (ANY-maze software). Furthermore, in the elevated plus maze, FMT-aged mice did not display significant differences in time spent in either arms of the maze compared to control groups (Fig. 4f, g). The values represent the mean ± SEM for each group (n = 10–12 mice/group)