Table 1 Baseline characteristics of subjects according to the gender and menopausal status
Clinical data | Pre-menopausal (n = 44) | Post-menopausal (n = 45) | Men (n = 42) | P |
|---|---|---|---|---|
Age | 41.9 [34.4-48.4] | 58.6 [55.4-59.6] | 46.1 [39.2-54.3] | < 0.001 |
Polycystic ovary syndrome (%) | 3 (7%) | 0 (0%) | 0 (0%) | 0.05 |
Alcohol intake (g/day) | 0.0 [0.0-2.1] | 0.86 [0.0-2.5] | 2.3 [0.0-12.3] | 0.003 |
Smoking (no, former, yes) (%) | 63.6, 27.3, 9.1 | 46.7, 44.4, 8.9 | 51.9, 35.9, 12.2 | 0.202 |
Obesity (%) | 61.4 | 55.6 | 57.1 | 0.849 |
BMI (kg/m2) | 39.5 [25.0-44.3] | 32.8 [24.4-41.4] | 34.1 [27.5-45.1] | 0.304 |
Fat mass (kg) | 46.3 [21.8-61.3] | 39.8 [22.6-50.3] | 34.5 [23.5-61.1] | 0.530 |
SBP (mmHg) | 128.5 (18.6) | 131.0 (18.7) | 133.5 (20.4) | 0.088 |
DBP (mmHg) | 73.5 (12.8) | 76.5 (9.3) | 76.0 (11.8) | 0.276 |
HDL cholesterol (mg/dL) | 52.0 [45.5-62.0] | 62.0 [51.5-72.5] | 48.5 [37.8-58.0] | < 0.001 |
Triglycerides (mg/dL) | 79.5 [58.7-106.7] | 96.0 [72.5-132.0] | 104 [67.5-162.7] | 0.071 |
Fasting plasma glucose (mg/dl) | 94.0 [88.0-98.8] | 96.0 [90.5-104.5] | 98.0 [90.8-104.0] | 0.197 |
HOMA-IR | 5.68 [2.56-8.02] | 3.01 [1.78-5.90] | 3.57 [2.35-6.44] | 0.051 |
IVGTT (80-120 min) (mg/dL) | 106.7 (8.18) | 103.1 (8.69) | 103.5 (9.16) | 0.162 |
M-clamp (mg/(kg·min)) | 5.30 [2.50-10.4] | 6.86 [4.60-10.3] | 5.01 [2.61-8.39] | 0.137 |
HbA1c (%) | 5.50 (0.29) | 5.56 (0.32) | 5.52 (0.29) | 0.606 |
hs-CRP (mg/dL) | 3.24 [0.91-9.49] | 2.53 [0.64-6.10] | 1.69 [0.74-3.14] | 0.065 |