Table 1 Study cohort metadata and genotype. This study cohort was extracted from the larger CDGEMM prospective longitudinal birth cohort study [33]
| Â | USA (n = 18) | Italy (n = 13) | Total (n = 31) |
|---|---|---|---|
Gender (%) | |||
 Male | 11 (61.1) | 7 (53.8) | 18 (58.0) |
 Female | 7 (38.9) | 6 (46.2) | 13 (42.0) |
Mode of delivery (%) | |||
 Vaginal | 11 (61.1) | 7 (53.8) | 18 (58.0) |
 C-section | 7 (38.9) | 6 (46.2) | 13 (42.0) |
Feeding type (4–6 months of age) (%) | |||
 Breastmilk only | 12 (66.7) | 4 (30.7) | 16 (51.6) |
 Formula only | 5 (27.8) | 6 (46.2) | 11 (35.5) |
 Both | 1 (5.5) | 3 (23.1) | 4 (12.9) |
Antibiotic exposure (%) | |||
 At delivery (mother) | 7 (38.9) | 2 (15.4) | 9 (29.0) |
 At birth (infant) | 2 (11.1) | 2 (15.4) | 4 (12.9) |
 Before 6 months of age (infant) | 0 (0.0) | 4 (30.8) | 4 (12.9) |
Genotype (%) | |||
 DQ2 homozygous | 6 (33.3) | 1 (7.7) | 7 (22.6) |
 DQ2 heterozygous | 6 (33.3) | 6 (46.2) | 12 (38.7) |
 DQ2/DQ8 | 3 (16.7) | 2 (15.4) | 5 (16.1) |
 DQ8 | 1 (5.5) | 1 (7.7) | 2 (6.5) |
 Negative | 2 (11.1) | 3 (23.1) | 5 (16.1) |
Relative with CD | |||
 Mother | 15 (83.3) | 7 (53.8) | 22 (70.9) |
 Father | 1 (5.5) | 1 (7.7) | 2 (6.5) |
 Sibling | 2 (11.1) | 5 (38.4) | 7 (22.6) |