Fig. 6

Longitudinal analysis of microbiota features for genetically predisposed infants a microbial species, b functional pathways, and c metabolites that are differentially abundant between each pair of time points (enrollment, 3 months, and 4–6 months) according to a paired Wilcoxon (Wilcoxon signed rank) test (p value < 0.05). Here, “Time1” denotes the earlier time point. In this figure, “u_s” denotes and unspecified species. Additional File 8 for grouping of pathways based on KEGG categorizations. See Additional File 9 for boxplots showing altered abundances for these pathways and metabolites