Fig. 3

Identification of enterotypes in the Korean gut archaeome. The faecal archaeal 16S rRNA gene sequences were prepared from Korean individuals. We subsampled 342 from the 381 archaeal-sequence–positive samples at a sampling depth of 10,000. a PCoA was generated based on the weighted UniFrac distance matrix of the archaeal 16S rRNA gene sequence data. Colour gradations show the relative abundances of the families Methanobacteriaceae (green), Haloferacaceae (red) and Methanomethylophilaceae (blue). b–d. Assortment of gut archaeal communities into enterotypes. b The optimal number of clusters was estimated at the family level by partitioning around medoids (PAM) clustering based on the Bray-Curtis dissimilarity matrix. c The relative abundance of the archaeal communities in all samples are presented according to the clusters and shown as a heat map. d Visualisation of enterotypes. The dots and numbers represent the abundance distributions of the archaeal taxa from individual samples and the centre of each enterotype, respectively