Skip to main content

Table 2 Associations of antimicrobial (AM) prescriptions (all AMs, and for amoxicillin, azithromycin, amoxicillin-clavulanate and phenoxymethylpenicillin AMs separately) with alpha-diversity, using the Shannon index and inverse Simpson index, in all the participants and separately in boys and girls using linear regression analysis

From: Antimicrobial drug use in the first decade of life influences saliva microbiota diversity and composition

 

Prescriptions of

All participants

Boys

Girls

n

Estimate

SE

p

n

Estimate

SE

p

n

Estimate

SE

p

Shannon

All AMs

5996

− 0.003

0.002

0.137

2957

− 0.005

0.002

0.045

3039

− 0.001

0.003

0.648

Amoxicillin

2622

0.002

0.004

0.685

1280

− 0.007

0.005

0.186

1342

0.011

0.006

0.079

Azithromycin

1495

− 0.015

0.005

0.002

783

− 0.003

0.006

0.623

712

− 0.032

0.008

< 0.001

Amoxicillin-clavulanate

1123

0.003

0.005

0.471

531

− 0.005

0.007

0.509

592

0.011

0.007

0.093

Phenoxymethylpenicillin

408

0.004

0.011

0.673

199

− 0.002

0.014

0.895

209

0.014

0.015

0.378

Inverse Simpson

All AMs

5996

− 0.013

0.020

0.500

2957

− 0.038

0.026

0.147

3039

0.006

0.029

0.848

Amoxicillin

2622

0.007

0.045

0.876

1280

− 0.053

0.060

0.379

1342

0.066

0.068

0.328

Azithromycin

1495

− 0.077

0.052

0.143

783

− 0.024

0.063

0.705

712

− 0.159

0.087

0.067

Amoxicillin-clavulanate

1123

0.016

0.054

0.770

531

− 0.066

0.078

0.393

592

0.080

0.075

0.282

Phenoxymethylpenicillin

408

0.077

0.118

0.513

199

0.042

0.158

0.791

209

0.135

0.174

0.439

  1. Significant results in bold
  2. Adjusted for age, gender (not in gender-specific analysis) and language. SE Std. error, n number of AM prescriptions