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Fig. 8 | Microbiome

Fig. 8

From: The extracellular vesicle of gut microbial Paenalcaligenes hominis is a risk factor for vagus nerve-mediated cognitive impairment

Fig. 8

Vagotomy inhibited the accumulation of Paenalcaligenes hominis extracellular vesicles (EVs), but not lipopolysaccharide (LPS), in the hippocampus of mice. A Effect on the accumulation of FITC-labeled EV and LPS. B Effects on the bacterial 16S rDNA levels in the hippocampus. EV and LPS were orally gavaged for 3 days in mice with or without vagotomy. Control mice with (Vx) and without vagotomy (NC) were treated with vehicle (saline) instead of bacterial suspension. Data values were indicated as mean ± SD (n = 6). Means with the same letters are not significantly different (p < 0.05). B One-way ANOVA with post hoc Bonferroni’s multiple comparisons test

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