Fig. 3

SPIEC-EASI cross-domain correlation network analysis of the skin microbiota. a Overall cross-domain network structure for the cheek and scalp sites (city combined) and skin condition. Taxa are represented by nodes and shaded by their domain (bacteria in orange, fungi in brown). Blue and red edges represent positive and negative correlations, respectively. Node size and edge thickness refer to OTU abundance and correlation strength, respectively. b Node degree distribution of networks for cheek and scalp microbiota, grouped by city and skin condition. Arrows indicate the decrease in peak degree distribution from healthy to affected skin sites for the respective cities. c Structure stability for microbial networks of cheek and scalp sites of different cities and skin phenotypes. Decrease in network stability is represented by percentage reduction of natural connectivity upon betweenness-ranked node attack removal