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Fig. 3 | Microbiome

Fig. 3

From: Bacteroides thetaiotaomicron-derived outer membrane vesicles promote regulatory dendritic cell responses in health but not in inflammatory bowel disease

Fig. 3

Lack of IL-10 response from colonic DC to Bt OMVs in ulcerative colitis. Following 20 h culture of LP cells from five proximal and five distal colon biopsies from UC patients with Bt OMVs 1010/mL or medium only, DC cytokine responses were examined by FACS. a Pooled data (n = 3) showing proportions of mDC expressing IL-6 (top left) and IL-10 (top right) and representative FACS plots from one UC patient (bottom). b Comparison of proportions of mDC expressing IL-6 (top) and IL-10 (bottom) in UC (n = 3) to HC (n = 6). Statistical significance was determined using unpaired t tests; *p < 0.05

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Microbiome

ISSN: 2049-2618

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