Table 2 Multidrug-resistant Gram-positive pathogens tested for sensitivity toward S. hominis S34-1 activity
From: Skin microbiota analysis-inspired development of novel anti-infectives
Type of species | Comment | Reference | Antibiogramsa |
|---|---|---|---|
CA-MRSAa (ST1) | Strain MW2 (USA400) | [17] | OXA, CFZ, PEN, CXM, FOX |
HA-MRSA (ST5) | Strain HS72, pathogenic, isolated from abscess | [16] | OXA, LVX, CLI, CFZ, FOS, ERY, AMK, PEN, GEN, FOX |
CA-MRSA (ST8) | SF8300 (USA300) | [18] | OXA, CFZ, ERY, PEN, CXM, FOX |
LA-MRSA (ST9) | Pathogenic, isolated from bovine mastitis | [19] | OXA, LVX, CLI, CFZ, ERY, TGC, PEN, CXM, FOX |
CA-MRSA (ST30) | Strain SF-1497 (USA1100) | [18] | OXA, CFZ, PEN, CXM, FOX |
HA-MRSA (ST36) | Strain SF 1208 (USA200) | [18] | OXA, LVX, CLI, CFZ, ERY, SAM, PEN, CXM, FOX |
CA-MRSA (ST59) | Strain RJ-2, pathogenic, isolated from skin infection | [15] | OXA, CLI, ERY, PEN, CXM, FOX |
CA-MRSA (ST72) | Strain CN1, South Korea | [20] | OXA, CFZ, ERY, PEN, CXM, FOX |
CA-MRSA (ST80) | Strain 07-02662, Germany | [21] | OXA, ERY, PEN, FOX |
HA-MRSA (ST239) | Strain HS770, isolated from sputum | [16] | OXA, LVX, CLI, CFZ, ERY, AMK, SAM |
CA-MRSA (ST398) | Pathogenic, isolated from blood | [22] | OXA, ERY, PEN, FOX |
Staphylococcus capitis | Pathogenic, isolated from pleural fluid | This study | OXA, PEN, CIP, SXT, MXF, LVX |
Staphylococcus epidermidis | Pathogenic, isolated from blood | This study | OXA, PEN, CIP, ERY, MXF, LVX |
Staphylococcus hominis | Pathogenic, isolated from blood | This study | OXA, PEN, ERY |
Streptococcus dysgalactiae | Pathogenic, isolated from sputum | This study | ERY |
Streptococcus agalactiae | Pathogenic, isolated from urine | This study | CLI, LVX, CIP, MXF |
Streptococcus salivarius | Pathogenic, isolated from blood | This study | PEN |
Streptococcus constellatus | Pathogenic, isolated from blood | This study | PEN |
Streptococcus pneumoniae | Pathogenic, isolated from sputum | This study | PEN, CLI, OXA, LVX, ERY, CLR |
VRE (Enterococcus faecium) | Pathogenic, isolated from catheter | This study | VAN, PEN, CIP, LVX, ERY, LVX, TEC, TET, AMP, MXF, GEN, CLI, FOF |
VRE (Enterococcus faecium) | Pathogenic, isolated from urine | This study | VAN, PEN, AMP, CIP, LVX, MXF, ERY, CLI |
VRE (Enterococcus faecium) | Pathogenic, isolated from urine | This study | VAN, PEN, CIP, LVX, ERY, LVX, TEC, AMP, MXF, STR, CLI, FOF |