Skip to main content

Table 2 Multidrug-resistant Gram-positive pathogens tested for sensitivity toward S. hominis S34-1 activity

From: Skin microbiota analysis-inspired development of novel anti-infectives

Type of speciesCommentReferenceAntibiogramsa
CA-MRSAa
(ST1)
Strain MW2
(USA400)
[17]OXA, CFZ, PEN, CXM, FOX
HA-MRSA
(ST5)
Strain HS72, pathogenic, isolated from abscess[16]OXA, LVX, CLI, CFZ, FOS, ERY, AMK, PEN, GEN, FOX
CA-MRSA (ST8)SF8300
(USA300)
[18]OXA, CFZ, ERY, PEN, CXM, FOX
LA-MRSA
(ST9)
Pathogenic, isolated from bovine mastitis[19]OXA, LVX, CLI, CFZ, ERY, TGC, PEN, CXM, FOX
CA-MRSA
(ST30)
Strain SF-1497
(USA1100)
[18]OXA, CFZ, PEN, CXM, FOX
HA-MRSA
(ST36)
Strain SF 1208
(USA200)
[18]OXA, LVX, CLI, CFZ, ERY, SAM, PEN, CXM, FOX
CA-MRSA (ST59)Strain RJ-2, pathogenic, isolated from skin infection[15]OXA, CLI, ERY, PEN, CXM, FOX
CA-MRSA
(ST72)
Strain CN1, South Korea[20]OXA, CFZ, ERY, PEN, CXM, FOX
CA-MRSA
(ST80)
Strain 07-02662, Germany[21]OXA, ERY, PEN, FOX
HA-MRSA
(ST239)
Strain HS770, isolated from sputum[16]OXA, LVX, CLI, CFZ, ERY, AMK, SAM
CA-MRSA
(ST398)
Pathogenic, isolated from blood[22]OXA, ERY, PEN, FOX
Staphylococcus capitisPathogenic, isolated from pleural fluidThis studyOXA, PEN, CIP, SXT, MXF, LVX
Staphylococcus epidermidisPathogenic, isolated from bloodThis studyOXA, PEN, CIP, ERY, MXF, LVX
Staphylococcus hominisPathogenic, isolated from bloodThis studyOXA, PEN, ERY
Streptococcus dysgalactiaePathogenic, isolated from sputumThis studyERY
Streptococcus agalactiaePathogenic, isolated from urineThis studyCLI, LVX, CIP, MXF
Streptococcus salivariusPathogenic, isolated from bloodThis studyPEN
Streptococcus constellatusPathogenic, isolated from bloodThis studyPEN
Streptococcus pneumoniaePathogenic, isolated from sputumThis studyPEN, CLI, OXA, LVX, ERY, CLR
VRE (Enterococcus faecium)Pathogenic, isolated from catheterThis studyVAN, PEN, CIP, LVX, ERY, LVX, TEC, TET, AMP, MXF, GEN, CLI, FOF
VRE (Enterococcus faecium)Pathogenic, isolated from urineThis studyVAN, PEN, AMP, CIP, LVX, MXF, ERY, CLI
VRE (Enterococcus faecium)Pathogenic, isolated from urineThis studyVAN, PEN, CIP, LVX, ERY, LVX, TEC, AMP, MXF, STR, CLI, FOF
  1. aAntibiograms were determined by disc diffusion on Mueller-Hinton agar according to Clinical and Laboratory Standards Institute guidelines
  2. Abbreviations: OXA oxacillin, PEN penicillin, LVX levofloxacin, CFZ cephazolin, CXM cefuroxime, FOX cefoxitin, CLI cephalexin, FOS fosfomycin, ERY erythromycin, AMK amikacin, GEN gentamicin, TGC tigecycline, SAM sulbactam/ampicillin, SXT sulphamethoxazole/trimethoprim, MXF moxifloxacin, CIP ciprofloxacin, TET tetracycline, CLR clarithromycin, VAN vancomycin, TEC teicoplanin, STR streptomycin, FOF nitrofurantoin, LA live-associated, CA community-associated, HA hospital-associated