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Table 2 List of antibiotic resistance genes retrieved from the Han River virome contigs

From: Freshwater viral metagenome reveals novel and functional phage-borne antibiotic resistance genes

Contig (ORF)a

ARG classification

ARG

% ident.

e value

Query cov. (%)

H6-C148-ORF17

Antibiotic inactivation

VatA

27.39

1.93 × 10−6

66

H7-C136-ORF18

Antibiotic inactivation

VatA

27.39

1.93 × 10−6

66

N1-C442-ORF2

Antibiotic inactivation

VatB

40.91

2.42 × 10−43

95

H6-C980-ORF4

Antibiotic inactivation

AAC(6’)-Is

29.41

7.38 × 10−7

72

H4-C737-ORF5

Antibiotic inactivation

AAC(6’)-Is

29.41

7.38 × 10−7

72

N3-C281-ORF7

Antibiotic inactivation

AAC(6’)-Iu

30.39

8.87 × 10−7

72

N3-C510-ORF10

Antibiotic inactivation

AAC(6’)-Iu

31.37

8.66 × 10−8

72

N1-C181-ORF5

Antibiotic inactivation

AAC(6’)-Iu

30.39

8.87 × 10−7

72

H6-C750-ORF4

Antibiotic inactivation

AAC(6’)-Iu

31.37

9.12 × 10−8

72

H1-C452-ORF7

Antibiotic inactivation

AAC(6’)-Iu

30.39

8.87 × 10−7

72

N3-C559-ORF4

Antibiotic inactivation

AAC(6’)-Iy

20.42

5.52 × 10−5

84

H4-C798-ORF18

Antibiotic inactivation

AAC(6’)-Iy

20.42

5.52 × 10−5

84

H7-C307-ORF22

Antibiotic inactivation

AAC(6’)-Iy

20.42

5.52 × 10−5

84

H1-C107-ORF42

Antibiotic inactivation

AAC(6’)-Iy

20.42

5.52 × 10−5

84

H4-C441-ORF28b

Antibiotic inactivation

β-lactamase

37.18

8.00 × 10−38

88

H4-C244-ORF21b

Antibiotic inactivation

β-lactamase

37.45

1.00 × 10−57

96

H4-C367-ORF18b

Antibiotic inactivation

β-lactamase

37.45

1.00 × 10−57

96

H1-C74-ORF21b

Antibiotic inactivation

β-lactamase

37.45

1.00 × 10−57

96

H1-C267-ORF1

Antibiotic target protection

QnrA3

28.78

8.13 × 10−5

65

H6-C122-ORF31

Antibiotic target alteration

DfrB2

67.31

6.88 × 10−21

83

H4-C9-ORF60

Antibiotic target alteration

DfrB2

67.31

6.88 × 10−21

83

H7-C8-ORF44

Antibiotic target alteration

DfrB2

67.31

6.88 × 10−21

83

H1-C119-ORF31

Antibiotic target alteration

DfrB2

67.31

6.88 × 1021

83

H6-C515-ORF10

Antibiotic target alteration

VanY

27.10

1.02 × 10−5

76

H4-C770-ORF17

Antibiotic target alteration

VanY

27.10

1.02 × 10−5

76

  1. aContig number (C) and ORF number (ORF) are listed after study site number
  2. bThe % identity, e value, and query coverage of β-lactamases have been retrieved from BLASTp against NCBI nr database