Skip to main content
Fig. 2 | Microbiome

Fig. 2

From: Mechanistic insights into the attenuation of intestinal inflammation and modulation of the gut microbiome by krill oil using in vitro and in vivo models

Fig. 2

Krill oil (KO) enhanced intracellular bacterial killing in macrophages and regulated the expression of various macrophage marker genes in vitro. a Genes and Gene Ontology (GO) terms related to monocyte differentiation. b KO reversed the effect of LPS on M1 macrophage related marker genes. c M2 macrophage activation related genes were upregulated by KO. d LPS-induced expression of IL12B (d) and CXCL10 (e) was significantly inhibited by KO and COX2 and IKK2 inhibitors, alone or in combination. f KO enhanced intracellular bacterial killing of Citrobacter rodentium as the number of the bacteria surviving the gentamicin protection assay was significantly reduced. ***p < 0.001; **p < 0.01; ###p < 0.001 (LPS vs. NC)

Back to article page

Microbiome

ISSN: 2049-2618

Contact us