Fig. 3
From: Lung function and microbiota diversity in cystic fibrosis
Comparison of microbiota diversity, dominance and composition when stratified by lung disease category. In each instance, relationships within the microbiota, core taxa and satellite taxa are given. Changes in (a) Fisher’s alpha index of diversity and (b) Berger-Parker dominance index with lung disease category (%FEV1). Boxplots show 25–75th interquartile (IQR) range with whiskers showing 1.5 times IQR. Black circles indicate individual patients and cross symbol represents the mean. Asterisks denote significant differences in diversity or dominance between two lung disease categories following both Kruskal-Wallis tests and Hedges’ d effect size analysis.(c) Variation in microbiota composition within (columns) and between (circles) lung disease categories using the Bray-Curtis index of similarity. Error bars represent standard deviation of the mean. Asterisks denote significant differences in composition between lung disease categories following one-way PERMANOVA tests with Bonferroni correction. Summary statistics for Kruskal-Wallis and PERMANOVA analyses are provided in supplementary Tables S2, S3 and S4. Hedges’ d effect size analyses are provided in Figure S1