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Table 2 Bacterial taxa associated with host infection status, at phylum and genus level, identified using the interpolated area under the receiver operating characteristic (ROC) curve (= AUC) in a random forest (RF) classifier. The predicted mean decreasing accuracy (MDA) score generated for each taxon, using the estimated RF model, is also shown. AUCs > 0.5 are not shown. In comparative analyses between gut microbial profiles of helminth-infected and -uninfected hosts, only phyla and genera making up > 1% and > 0.5% of the overall microbiota, respectively, in at least one group are reported

From: MICHELINdb: a web-based tool for mining of helminth-microbiota interaction datasets, and a meta-analysis of current research

 

Relative abundance (%)

Phylum

Genus

AUC

Fold change

Uninfected

Infected

Non-rodents

Actinobacteria

Collinsella

0.56

− 0.64

2.37

3.69

Actinobacteria

Bifidobacterium

0.54

0.85

2.68

2.26

Bacteroidetes

 

0.58

1.18

18.83

16.01

 

Bacteroides

0.60

0.55

6.97

3.83

Parabacteroides

0.58

0.71

0.51

0.37

Alloprevotella

0.51

0.69

1.05

0.72

Firmicutes

 

0.56

− 1.10

48.94

54.05

Streptococcus

0.52

0.65

2.58

1.69

Catenibacterium

0.53

− 0.41

0.33

0.80

Holdemanella

0.57

− 0.51

0.76

1.48

Lachnoclostridium

0.52

0.98

0.58

0.57

Subdoligranulum

0.55

0.83

2.39

1.99

Veillonella

0.54

− 0.46

0.29

0.62

Peptoclostridium

0.55

− 0.48

0.84

1.76

Blautia

0.54

− 0.81

1.77

2.19

Megamonas

0.54

− 0.45

0.35

0.78

Romboutsia

0.52

− 0.72

0.65

0.89

Faecalibacterium

0.55

0.88

2.64

2.32

Dialister

0.54

0.78

0.97

0.76

Turicibacter

0.52

− 0.29

0.16

0.56

Fusobacteria

 

0.55

− 1.21

1.70

2.06

Fusobacterium

0.57

− 0.91

1.60

1.77

Rodents

Actinobacteria

 

0.54

1.33

1.27

0.95

Bifidobacterium

0.62

1.66

0.63

0.38

Bacteroidetes

 

0.68

1.51

46.02

30.4

Alistipes

0.57

− 1.08

1.66

1.79

Bacteroides

0.61

− 1.06

1.06

1.13

Odoribacter

0.57

− 1.5

0.53

0.8

Firmicutes

 

0.65

− 1.25

48.33

60.46

Turicibacter

0.58

5.44

1.83

0.34

Lactobacillus

0.69

− 2.2

15.37

33.82

Faecalibaculum

0.62

1.98

3.01

1.52

Dubosiella

0.61

2.97

1.24

0.42

Candidatus Arthromitus

0.62

− 59.75

0.01

0.74

Roseburia

0.59

1.05

0.63

0.6

Proteobacteria

Desulfovibrio

0.62

1.94

0.64

0.33

Helicobacter

0.57

− 7.69

0.1

0.74

Verrucomicrobia

 

0.58

− 3.09

0.7

2.16

Akkermansia

0.59

− 3.14

0.68

2.14