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Table 2 Bacterial taxa associated with host infection status, at phylum and genus level, identified using the interpolated area under the receiver operating characteristic (ROC) curve (= AUC) in a random forest (RF) classifier. The predicted mean decreasing accuracy (MDA) score generated for each taxon, using the estimated RF model, is also shown. AUCs > 0.5 are not shown. In comparative analyses between gut microbial profiles of helminth-infected and -uninfected hosts, only phyla and genera making up > 1% and > 0.5% of the overall microbiota, respectively, in at least one group are reported

From: MICHELINdb: a web-based tool for mining of helminth-microbiota interaction datasets, and a meta-analysis of current research

  Relative abundance (%)
Phylum Genus AUC Fold change Uninfected Infected
Non-rodents
Actinobacteria Collinsella 0.56 − 0.64 2.37 3.69
Actinobacteria Bifidobacterium 0.54 0.85 2.68 2.26
Bacteroidetes   0.58 1.18 18.83 16.01
  Bacteroides 0.60 0.55 6.97 3.83
Parabacteroides 0.58 0.71 0.51 0.37
Alloprevotella 0.51 0.69 1.05 0.72
Firmicutes   0.56 − 1.10 48.94 54.05
Streptococcus 0.52 0.65 2.58 1.69
Catenibacterium 0.53 − 0.41 0.33 0.80
Holdemanella 0.57 − 0.51 0.76 1.48
Lachnoclostridium 0.52 0.98 0.58 0.57
Subdoligranulum 0.55 0.83 2.39 1.99
Veillonella 0.54 − 0.46 0.29 0.62
Peptoclostridium 0.55 − 0.48 0.84 1.76
Blautia 0.54 − 0.81 1.77 2.19
Megamonas 0.54 − 0.45 0.35 0.78
Romboutsia 0.52 − 0.72 0.65 0.89
Faecalibacterium 0.55 0.88 2.64 2.32
Dialister 0.54 0.78 0.97 0.76
Turicibacter 0.52 − 0.29 0.16 0.56
Fusobacteria   0.55 − 1.21 1.70 2.06
Fusobacterium 0.57 − 0.91 1.60 1.77
Rodents
Actinobacteria   0.54 1.33 1.27 0.95
Bifidobacterium 0.62 1.66 0.63 0.38
Bacteroidetes   0.68 1.51 46.02 30.4
Alistipes 0.57 − 1.08 1.66 1.79
Bacteroides 0.61 − 1.06 1.06 1.13
Odoribacter 0.57 − 1.5 0.53 0.8
Firmicutes   0.65 − 1.25 48.33 60.46
Turicibacter 0.58 5.44 1.83 0.34
Lactobacillus 0.69 − 2.2 15.37 33.82
Faecalibaculum 0.62 1.98 3.01 1.52
Dubosiella 0.61 2.97 1.24 0.42
Candidatus Arthromitus 0.62 − 59.75 0.01 0.74
Roseburia 0.59 1.05 0.63 0.6
Proteobacteria Desulfovibrio 0.62 1.94 0.64 0.33
Helicobacter 0.57 − 7.69 0.1 0.74
Verrucomicrobia   0.58 − 3.09 0.7 2.16
Akkermansia 0.59 − 3.14 0.68 2.14