TY - JOUR AU - Lee, Kihyun AU - Kim, Dae-Wi AU - Lee, Do-Hoon AU - Kim, Yong-Seok AU - Bu, Ji-Hye AU - Cha, Ju-Hee AU - Thawng, Cung Nawl AU - Hwang, Eun-Mi AU - Seong, Hoon Je AU - Sul, Woo Jun AU - Wellington, Elizabeth M. H. AU - Quince, Christopher AU - Cha, Chang-Jun PY - 2020 DA - 2020/01/07 TI - Mobile resistome of human gut and pathogen drives anthropogenic bloom of antibiotic resistance JO - Microbiome SP - 2 VL - 8 IS - 1 AB - The impact of human activities on the environmental resistome has been documented in many studies, but there remains the controversial question of whether the increased antibiotic resistance observed in anthropogenically impacted environments is just a result of contamination by resistant fecal microbes or is mediated by indigenous environmental organisms. Here, to determine exactly how anthropogenic influences shape the environmental resistome, we resolved the microbiome, resistome, and mobilome of the planktonic microbial communities along a single river, the Han, which spans a gradient of human activities. SN - 2049-2618 UR - https://doi.org/10.1186/s40168-019-0774-7 DO - 10.1186/s40168-019-0774-7 ID - Lee2020 ER -