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Table 2 Analysis of body composition, food intake, and weight in gnotobiotic mice colonized with consortium A or consortium B

From: Applying indirect open-circuit calorimetry to study energy expenditure in gnotobiotic mice harboring different human gut microbial communities

Body composition (defined by qMR)

dpg

Consortium A

Consortium B

p value*

Mean ± SD

Mean ± SD

Fat mass (grams)

15

4.10 ± 0.37

4.90 ± 0.38

p < 0.05

29

4.21 ± 0.52

5.23 ± 0.69

p < 0.01

Lean body mass (grams)

15

21.58 ± 1.27

20.82 ± 1.43

ns

29

21.67 ± 0.93

21.65 ± 1.44

ns

Food intake (grams)

4

4.22 ± 0.97

4.48 ± 2.16

ns

7

3.63 ± 0.52

2.77 ± 0.41

ns

11

2.90 ± 0.55

2.51 ± 0.53

ns

15

3.00 ± 0.46

3.00 ± 0.39

ns

18

2.88 ± 0.48

2.73 ± 0.31

ns

21

2.88 ± 0.23

2.87 ± 0.35

ns

25

3.38 ± 0.62

3.08 ± 0.73

ns

29

3.42 ± 0.90

3.25 ± 0.47

ns

32

3.15 ± 0.37

2.88 ± 0.47

ns

Weight (normalized to starting weight)

4

1.02 ± 0.04 (6)

1.00 ± 0.03 (6)

ns

7

1.02 ± 0.04 (6)

1.00 ± 0.03 (6)

ns

11

1.02 ± 0.03 (6)

1.01 ± 0.04 (6)

ns

15

1.01 ± 0.03 (6)

1.01 ± 0.04 (6)

ns

18

1.01 ± 0.04 (6)

1.02 ± 0.03 (6)

ns

21

1.02 ± 0.05 (6)

1.02 ± 0.04 (6)

ns

25

1.04 ± 0.05 (6)

1.03 ± 0.04 (6)

ns

29

1.02 ± 0.04 (6)

1.05 ± 0.04 (6)

ns

32

1.03 ± 0.06 (6)

1.06 ± 0.04 (6)

ns

  1. *2-way ANOVA (n = 6 animals/group)