Fig. 8

Quantitative effects of removing OTUs with features of contaminants on mock community samples. a–d. Bar chart showing the proportion of OTUs that are negatively correlated with density (Feature 1, F1) or that were not reproducible between technical replicates (Feature 2, F2), along with the proportion they represent within their target groups (contaminant or true taxa). The black line indicates the cumulative amount within each target group (contaminants or true taxa) corresponding to the OTUs identified with each filtering approach. e Comparison of post-filtering effect on sequencing accuracy across a range of densities. f Sequencing precision across range of densities before and after removal by feature