Skip to main content
Fig. 7 | Microbiome

Fig. 7

From: Antibiotic-modulated microbiome suppresses lethal inflammation and prolongs lifespan in Treg-deficient mice

Fig. 7

Mechanisms of protection of antibiotic-modulated microbiome against Treg deficiency-mediated lethal inflammation. Treg deficiency shapes gut microbiota and bile acid metabolism and induces IL-6 expression resulting in lethal inflammation and early death (left). Antibiotics modulate gut microbiota and bile acid metabolism and protect against Treg deficiency-induced lethal inflammation by suppressing IL-6 level (right)

Back to article page