Fig. 5

IL-6 blockade increases survival and inhibits inflammation in scurfy mice. a Scheme for IL-6 antibody treatment on SF mice for sample analysis and survival observation. b Survival curves of SF mice with IgG (SF∙IgG) or IL-6 antibody (SF∙aIL-6) treatment (n = 7–8). c Representative H&E staining of the liver and lung from SF∙IgG and SF∙aIL-6 mice (n = 6–9). d Quantitation of inflammatory infiltrates in the liver and lung of SF∙IgG and SF∙aIL-6 mice (n = 6–9). e Plasma levels of IL-6, IL-10, and IL-2 in SF∙IgG and SF∙aIL-6 mice (n = 6–9). Data are presented as mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001