Fig. 2

Antibiotics alter the gut microbiota in scurfy mice. a Gut microbial Chao1 alpha diversity analysis, comparing groups of WT, SF, SFA, SFM, and SFV mice (n = 6–9). b Unweighted UniFrac-based 3D PCoA analysis of the gut microbiota of WT, SF, SFA, SFM, and SFV mice (n = 6–9). c Relative abundance of the gut microbiota at the phylum level from WT, SF, SFA, SFM, and SFV mice. d Cladogram of the gut microbiota from WT, SF, SFA, SFM, and SFV mice. The diameter of each circle is proportional to the abundance of the taxon. The color represents which branch of the phylogenetic tree more significantly represents a certain group. Labeled nodes highlighted in each color are significantly more abundant in that branch, respectively. Nodes remaining light green indicate taxa that were not significantly differentially represented. Only differentially abundant taxa at the genus or higher taxonomic ranks were indicated. Data are presented as mean ± SEM. *p < 0.05, ***p < 0.001