Fig. 5

Results of genome-wide association study between host genetic variants and microbiome diversity metrics. a Manhattan plot for Simpson’s diversity metric (representative α-diversity metric). The dashed horizontal line denotes the genome-wide significance threshold (P_α-threshold < 1.25 × 10⁻⁸). b Manhattan plot for Bray-Curtis dissimilarity matrix (representative ß-diversity index). The dashed horizontal line denotes the genome-wide significance threshold (P_β-threshold < 1.67 × 10⁻⁸)