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Table 1 Metabolites found to be dominant in regular SPF and CL-treated mouse intestines and their impacts on V. cholerae growth

From: Commensal-derived metabolites govern Vibrio cholerae pathogenesis in host intestine

  1. Twenty-seven metabolites that were present exclusively in either group were selected among 273 compounds. Metabolites detected most abundantly in the control group (No.1~13) or in the CL-treated group (No.14~27) are listed in the order of quantity. The growth-inhibiting or growth-promoting capability of a given metabolite is displayed semi-qualitatively with a minus (−) or plus (+) sign, respectively. For example, “+” indicates a metabolite with mild growth-promoting capability, whereas “---” indicates that the metabolite induced strong growth suppression. ND not detected, NT not tested, m/z mass-to-charge ratio, MT migration time, RT retention time, Vc Vibrio cholerae. Relative quantity of a metabolite is calculated by the equation: (peak area of the metabolite)/(peak areas of internal standards × sample amount). Peaks are assigned based on the signal-to-noise ratio (S/N) of 3 or above.