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Fig. 3 | Microbiome

Fig. 3

From: Diet-induced remission in chronic enteropathy is associated with altered microbial community structure and synthesis of secondary bile acids

Fig. 3

Diet-induced remission is associated with metabolic reprogramming and increased levels of secondary bile acids. a PCA analysis of UniPathway pathways based on the results of HUMAnN2 analysis for DR animals. b The first principal component (dim 2) from a, for all time points. c Heatmap showing the relative abundances of genes in secondary bile acid biosynthesis pathway after diet in DR animals. d Relative abundance of the pathway for secondary bile acid biosynthesis, predicted based on metagenomic data for DR animals. e–h Levels of deoxycholic (e) and lithocholic (f) acid measured in the stool of DR animals and NDR animals (g, h). ns, not significant. *P < 0.05, **P < 0.01 using Hotelling’s T-squared test for a or the two-sided Wilcoxon signed-rank test for other panels

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