Fig. 5

Comparison of COG categories between plasmids and chromosomes. The frequency of COGs (clusters of orthologous groups) is compared between 315 relatively high-abundance plasmid clusters and 249 chromosomes (≥ 0.1% average abundance) in the IGCJ dataset. COG categories with significant differences in enrichment between plasmids and chromosomes are marked with asterisks (p < 0.05, Fisher’s exact test). Biological functions are abbreviated by letters; X: Mobilome: prophages, transposons; S: function unknown; P: inorganic ion transport and metabolism; V: defence mechanisms; U: intracellular trafficking, secretion, and vesicular transport; L: replication, recombination and repair; R: general function prediction only; K: transcription; O: posttranslational modification, protein turnover, chaperones; M: cell wall/membrane/envelope biogenesis; G: carbohydrate transport and metabolism; T: signal transduction mechanisms; J: translation, ribosomal structure and biogenesis; N: cell motility; H: coenzyme transport and metabolism; C: energy production and conversion; Q: secondary metabolite biogenesis; W: extracellular structures; D: cell cycle control, cell division, chromosome partitioning; E: amino acid transport and metabolism; I: lipid transport and metabolism, transport and catabolism; F: nucleotide transport and metabolism