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Fig. 2 | Microbiome

Fig. 2

From: Gut microbiota from NLRP3-deficient mice ameliorates depressive-like behaviors by regulating astrocyte dysfunction via circHIPK2

Fig. 2

NLRP3 inflammasome deficiency affected the gut microbiota composition. a Three-dimensional PCoA of unweighted UniFrac distances showed obvious differences in the gut microbiota composition between WT and NLRP3 KO mice. Heatmap of the 120 discriminative OTUs between WT and NLRP3 KO mice. Each OTU ID and taxonomic assignment is provided to the right of the heatmap. b Relative abundances of genera significantly altered by NLRP3 inflammasome deficiency in the gut microbiota. N = 14 mice/group. **p < 0.01 and ***p < 0.001 vs. the WT group using the Mann-Whitney test

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Microbiome

ISSN: 2049-2618

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