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Fig. 2 | Microbiome

Fig. 2

From: Pregnancy and lactation interfere with the response of autoimmunity to modulation of gut microbiota

Fig. 2

Vancomycin-mediated downregulation of regulatory immune response in PP MRL/lpr mice. a Left: percentage of IL-6 producing cells in the spleen. Right: serum level of IL-6. Both were at 15 weeks of age. b Percentage of DN-T cell (CD3+CD4CD8) and CD4+ T cells (CD3+CD4+CD8) in the spleen at the 15 weeks of age (n ≥ 6 per group). c Representative FACS plots of IL-17 producing T cells. d Percentage of Th17 cells and IL-17 producing T cells (CD3+IL-17+) in the spleen at the 15 weeks of age (n ≥ 6 per group). e Percentage of Treg (CD3+CD4+Foxp3+) and B10 (CD19+IL-10+) cells in the spleen at the 15 weeks of age (n ≥ 6 per group). f Level of IL-10 in mouse serum at the 15 weeks of age (n ≥ 7 per group). g Level of IDO in mouse serum at the 15 weeks and 11 weeks of age (n ≥ 4 per group). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, n.s. not statistically significant

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