TY - JOUR AU - Pan, Hudan AU - Guo, Ruijin AU - Ju, Yanmei AU - Wang, Qi AU - Zhu, Jie AU - Xie, Ying AU - Zheng, Yanfang AU - Li, Ting AU - Liu, Zhongqiu AU - Lu, Linlin AU - Li, Fei AU - Tong, Bin AU - Xiao, Liang AU - Xu, Xun AU - Leung, Elaine Lai-Han AU - Li, Runze AU - Yang, Huanming AU - Wang, Jian AU - Zhou, Hua AU - Jia, Huijue AU - Liu, Liang PY - 2019 DA - 2019/07/17 TI - A single bacterium restores the microbiome dysbiosis to protect bones from destruction in a rat model of rheumatoid arthritis JO - Microbiome SP - 107 VL - 7 IS - 1 AB - Early treatment is key for optimizing the therapeutic success of drugs, and the current initiating treatment that blocks the progression of bone destruction during the pre-arthritic stages remains unsatisfactory. The microbial disorder in rheumatoid arthritis (RA) patients is significantly reversed with effective treatment. Modulating aberrant gut microbiomes into a healthy state is a potential therapeutic approach for preventing bone damage. SN - 2049-2618 UR - https://doi.org/10.1186/s40168-019-0719-1 DO - 10.1186/s40168-019-0719-1 ID - Pan2019 ER -